Senior Technician/Research Associate – Cell Line Development

Agenus Overview

Agenus is a pioneer in the emerging field of Immuno-oncology. For over two decades, Agenus has been creating and advancing patient-specific anticancer vaccines in the effort to harness the power of the immune system to control and eradicate cancer. We now have a portfolio of innovative approaches that include checkpoint modulators, personalized anticancer vaccines and powerful adjuvants in all stages of discovery and clinical development. We are dedicated scientists, researchers, biotechnologists, physicians, and businesspeople working together toward one goal: minimize the burden of cancers and infections by helping the body heal itself through the power of science.

 The work we do at Agenus is cutting edge and deeply motivating. We believe passionately in our technology, in our pipeline, and in our responsibility to deliver on the promise of immunology to treat cancer and infectious disease. Our environment fosters innovation and leadership at every level. We encourage people to think and dream big. We provide the opportunity to apply your many talents and develop your career in creative and sometimes unconventional ways. If you’re looking for an inspired environment, passionate colleagues, and a culture that nurtures learning, innovation, and team success, we invite you to join us.

 We are looking for an enthusiastic, flexible Senior Technician / Research Associate to join the Cell Line Development team at our Cambridge site in the UK. This position plays a key role in progressing our research activities and generation of high expressing clonal cell lines for delivery to our Manufacturing plant at Berkley, California.

Role Responsibilities

The scope of hands-on involvement will cover molecular and cell biology activities for generating mammalian cell lines expressing recombinant proteins, including:

Co-ordinating requests and materials for transient and stable cell line protein expression.

Maintaining stocks of mammalian cell culture (incl. HEK293, CHO and Jurkat).

Routine laboratory procedures such as vector construction, DNA purification and quantification, bacterial transformation, and DNA sequencing and analysis. 

Managing resources for a small tissue culture lab.

Concisely and in a timely manner document experiments and results using electronic laboratory notebooks.

Contribute to the development of protocols.

In addition, you will have a keen eye for detail, a willingness to learn and a “can do” attitude. You will work and communicate well within a small team and be responsible for coordinating with facilities staff to ensure the smooth running of the tissue culture lab.

Qualifications

A BSc or MSc degree, or native equivalent, in a biology or biotechnology discipline or 1 to 3 years of relevant experience gained from working in industry.

Experience

Experience with and maintenance of cell culture using aseptic techniques.

Some experience in molecular biology would be advantageous, but training can be provided for the right candidate.

Confident grasp of software packages such as Microsoft Office and data recording. Further experience with related software packages a benefit.

Profile

Have a flexible approach to changing demands by assisting colleagues during peak activities.

An ability to work in a flexible, collaborative style with colleagues and teams.

Highly organized, able to prioritize work, work well under pressure and meet deadlines.